What are the leading causes of death in Mississippi?

Data updated July 19, 2024
Heart disease, cancer, and accidents were the leading causes of death in Mississippi in 2022. Of the 17,890 deaths that year, 47% were due to one of these three causes. The fourth and fifth most common causes were COVID-19 and chronic lower respiratory diseases.
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In 2022

23%

of deaths were from heart disease
In 2022

18%

of deaths were from cancer
In 2022

6%

of deaths were from accidents
For every 100,000 people living in Mississippi, 301 people died from heart disease and 227 died from cancer in 2022. The top five leading causes of death account for 59% of all deaths in 2022.

The leading causes of death in Mississippi are consistently heart disease and cancer.

2022's top five causes of death per 100,000 people in Mississippi

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The leading causes of death vary among age groups; older people are more likely to die in general, and more likely to succumb to illness than accidents. Accidents include accidental poisonings, or accidental drug overdoses, and motor vehicle accidents. For people over 45, the leading causes of death are heart disease and cancer. Accidents make up a larger share of the deaths of people under 45, accounting for 31% of total deaths in people ages 18 to 44. Accidental drug overdoses make up 15% of total deaths in this age group. In children, accidents account for 31% of deaths.

The impact of the top causes of death varies across age groups.

Percentage of deaths by cause and age group in 2022 in Mississippi

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