How many people live in Mississippi County, MO?
Updated Apr. 6, 2026Refreshed annually
In 2024, there were about 11,800 people living in Mississippi County, MO. That makes Mississippi County the 77th-most populous county in Missouri. It is home to 0.19% of people living in the state.
11.8K
population of Mississippi County, MO (2024)
0.19%
County share of the Missouri population (2024)
About 11,800 people lived in Mississippi County, MO in 2024.
Population estimates, 2000–2024
What are Mississippi County, MO’s age demographics?
About 2,300 Mississippi County residents are aged 65 and older in 2024. That represents 19.3% of its population. For comparison, the age group represents 18.8% of Missouri’s population and 18% in the US overall.
Another 2,700 Mississippi County, MO residents, or 22.8% of the population, were children under 18. For comparison, the age group represents 22% of Missouri’s population and 21.6% in the US overall.
A lower share of Mississippi County, MO's population is aged 25–44 than the US as a whole.
Population estimates by age group, (2024)
What are Mississippi County, MO’s racial and ethnic demographics?
Non-Hispanic white residents make up 71.8% of the Mississippi County, MO population, higher than the national share of 57.5%. Mississippi County, MO also has a larger share of people identifying as non-Hispanic Black or African American (22.8%) than the US overall (12.6%).
In contrast, Mississippi County’s Hispanic population accounts for 2.5%, below the 20% nationwide, and the non-Hispanic Asian population makes up 0.26% of the county, compared with 6.5% nationally.
Racial and ethnic make up differ based on location. These figures reflect how people identified their race alone (not in combination with other races), and separate out Hispanic or Latino ethnicity, following Census reporting standards.
Mississippi County, MO has a higher share of a non-Hispanic Black or African American population than Missouri as a whole.
Population estimates by race and ethnicity, (2024)
The largest city or town in Mississippi County, MO is Charleston with about 4,400 residents in 2024.
Cities and towns in Mississippi County, MO ranked by population
Population (2024), includes only portions within county
| City or town | Population | |
|---|---|---|
| 1. | Charleston | 4,447 |
| 2. | East Prairie | 2,859 |
| 3. | Bertrand | 704 |
| 4. | Wyatt | 207 |
| 5. | Anniston | 179 |
| 6. | Wilson City | 75 |
| 7. | Miner (pt.) | |
| 8. | Balance of Mississippi County | 3,279 |
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Methodology
USAFacts standardizes data, in areas such as time and demographics, to make it easier to understand and compare.
The analysis was generated with the help of AI and reviewed by USAFacts for accuracy.
Page sources
USAFacts endeavors to share the most up-to-date information available. We sourced the data on this page directly from government agencies; however, the intervals at which agencies publish updated data vary.
