How many people live in Issaquena County, MS?
Updated Apr. 6, 2026Refreshed annually
In 2024, there were about 1,300 people living in Issaquena County, MS. That makes Issaquena County the 82nd-most populous county in Mississippi. It is home to 0.04% of people living in the state.
1.3K
population of Issaquena County, MS (2024)
0.04%
County share of the Mississippi population (2024)
About 1,300 people lived in Issaquena County, MS in 2024.
Population estimates, 2000–2024
What are Issaquena County, MS’s age demographics?
About 197 Issaquena County residents are aged 65 and older in 2024. That represents 15.2% of its population. For comparison, the age group represents 18% of Mississippi’s population and 18% in the US overall.
Another 78 Issaquena County residents, or 6% of the population, were children under 18. For comparison, the age group represents 23% of Mississippi’s population and 21.6% in the US overall.
A lower share of Issaquena County, MS's population is aged under 18 than the US as a whole.
Population estimates by age group, (2024)
What are Issaquena County, MS’s racial and ethnic demographics?
Non-Hispanic Black or African American residents make up 62.2% of the Issaquena County, MS population, higher than the national share of 12.6%.
In contrast, Issaquena County’s non-Hispanic white population accounts for 28.2%, below the 57.5% nationwide, and the Hispanic population makes up 8.5% of the county, compared with 20% nationally.
Racial and ethnic make up differ based on location. These figures reflect how people identified their race alone (not in combination with other races), and separate out Hispanic or Latino ethnicity, following Census reporting standards.
Issaquena County, MS has a higher share of a non-Hispanic Black or African American population than Mississippi as a whole.
Population estimates by race and ethnicity, (2024)
The largest city or town in Issaquena County, MS is Mayersville with about 464 residents in 2024.
Cities and towns in Issaquena County, MS ranked by population
Population (2024), includes only portions within county
| City or town | Population | |
|---|---|---|
| 1. | Mayersville | 464 |
| 2. | Balance of Issaquena County | 831 |
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Methodology
USAFacts standardizes data, in areas such as time and demographics, to make it easier to understand and compare.
The analysis was generated with the help of AI and reviewed by USAFacts for accuracy.
Page sources
USAFacts endeavors to share the most up-to-date information available. We sourced the data on this page directly from government agencies; however, the intervals at which agencies publish updated data vary.