How many drug overdose deaths happen every year in South Dakota?
Updated May. 6, 2026Refreshed annually
There were 98 overdose deaths in 2024. That means that for every 100,000 people living in the state, 10.6 died of drug overdose. This was the 2nd highest the drug overdose death rate has been in the state since data from 2000 became available.
In 2024
11
per 100,000 people died of overdoses
In 2024
98
people died of overdoses
Unadjusted data about the nation is a useful starting point, but age-adjusted data tells a more complete story. Age-adjusting accounts for differences in age distributions across populations, which is crucial when comparing health outcomes since age is a major risk factor for many conditions. This adjustment enables fairer comparisons of mortality rates between different groups or over time. The rest of the data on this page is age-adjusted.
In 2024, South Dakota had a drug overdose death rate lower than the US rate overall, nearly 48% lower. The drug overdose death rate in South Dakota increased in 12 of the last 24 years in which data is available. The overdose death rate increased 13% since 2019 and increased 53% since 2014.
In 2024, South Dakota had a drug overdose death rate lower than the US rate.
Drug-involved overdose deaths in South Dakota, age-adjusted rate per 100,000 people
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What drugs are most commonly involved in drug overdose deaths?
The rise in drug overdose deaths nationally has been due to growing use of fentanyl and other synthetic opioids, however, this may vary by state. In 2024, methamphetamine has been involved in more overdose deaths than any other drug, making up 42% of total overdose deaths in South Dakota. The rates of drug overdose deaths involving Fentanyl and other synthetic opioids and Methamphetamine increased 2.4 and 1.6 times, between 2018 and 2024 and 2017 and 2024, respectively.
In 2024, methamphetamine was involved in more overdose deaths than any other drug.
Drug-involved overdose deaths in South Dakota, age-adjusted rate per 100,000 people
How do drug overdose deaths vary by county in South Dakota?
Drug overdose death rates can vary across counties. In 2024, the death rate for overdoses in South Dakota ranged from 13.8 per 100,000 in Pennington County to 14.9 per 100,000 in Minnehaha County.
Occasionally, the Centers for Disease Control and Prevention will mark data as either suppressed or unreliable. Suppression occurs when data does not meet confidentiality requirements. As a result, data may not be available for every county in this state. Age-adjusted data is also not available at the county level. County-level tables reflect the most recent year of available data.
Drug-involved overdose deaths per 100,000 people (2024)
| 1. | Minnehaha County | 14.9 |
| 2. | Pennington County | 13.8 |
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Methodology
USAFacts standardizes data, in areas such as time and demographics, to make it easier to understand and compare.
The analysis was generated with the help of AI and reviewed by USAFacts for accuracy.
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USAFacts endeavors to share the most up-to-date information available. We sourced the data on this page directly from government agencies; however, the intervals at which agencies publish updated data vary.
